After a somewhat mysterious sequence of events, an oceanic flight from Sydney to LA crashes on what appears to be a deserted island. The chance of being found and rescued is fairly small, so the survivors have to cope with a set of challenges. They have to learn to survive on the island, a mysterious place with enough dangers on its own. Also, they have to learn to live with each other if any success is to be expected. And finally, they have to live with themselves and their pasts. Interwoven with the events on the islands are flashbacks to the pasts of 14 main characters. Step by step, we learn a little more about their diverse and unexpected pasts as the group's quest to survive takes shape.